2024/25 Undergraduate Module Catalogue

MEDI2222 Clinical Pathology

Module manager: Dr Richard Bishop
Email: R.I.Bishop@leeds.ac.uk

Taught: Semester 2 (Jan to Jun) View Timetable

Year running 2024/25

Pre-requisite qualifications

Successful completion of Year 1 MBChB

Co-requisites

MEDI2201 Control and Movement
MEDI2202 Individuals and Populations 2
MEDI2217 Research, Evaluation and Special Studies 2
MEDI2218 Innovation, Development, Enterprise, Leadership and Safety 2
MEDI2219 Campus to Clinic 2
MEDI2220 RESS 2 Special Studies Project
MEDI2221 Essential Medical Science
MEDI2222 Clinical Pathology

Module replaces

MEDI2200 BMS

This module is not approved as a discovery module

Objectives

On completion of this module, students should be able to ...

1) Demonstrate knowledge of biochemistry, physiology, pathogenesis and anatomy so that it can be applied in the clinical setting to inform the investigation, diagnosis, management and monitoring of commonly occurring or important illustrative diseases.
2) Appreciate fully the principles of clinical pathology in order to effectively engage in clinical placement teaching in Yrs 3-5.
3) Identify the effective use of hospital pathology laboratories to justify the selection of tests and develop a critical attitude to their use.
4) Link their understanding to inform the diagnosis, management and treatment of patients and to control infection in the hospital environment.

Learning outcomes

The module is taught in the form of five separate strands; systematic pathology, microbiology and infection, haematology, clinical immunology. By the end of the module students should be able to understand and describe:

1) Important and illustrative diseases as they relate to different organ systems within the body.
2) The aetiology, pathogenesis, diagnosis, treatment and prevention of infection.
3) Disorders of the cellular and non-cellular components of the blood.
4) The role of the immune system in disease.
5) The diagnosis of disease from the chemical changes that occur in tissues and fluids.

Skills outcomes

1) Basic histopathology.
2) Use and interpretation of clinical laboratory testing.

Syllabus

Students are provided with an integrated scientific and clinical understanding of disease through a consideration of the aetiology, pathogenesis, diagnosis, treatment and prevention of important diseases, based upon the disciplines of systematic pathology, microbiology, haematology, clinical immunology and chemical pathology.

Systematic Pathology

Alimentary system, cardiovascular system, respiratory system, breast, female genital system, male genital system, hepatobiliary system, bone and joint pathology, skin, urinary system, diseases seen in infants and children, central and peripheral nervous system, diseases of the head and neck, endocrine system.

Microbiology and Infection

Micro-organisms, host-pathogen relationships, diagnosis of infection, treatment of infection, infection prevention and control.

Haematology

Physiology of blood, use of the laboratory, mechanisms of anaemia, thrombocytopenia, haematinic deficiency and the anaemia of chronic disease, thalassaemias and haemoglobinopathies, disorders of white cells, obstetric haematology, paediatric haematology, haemostasis overview, thrombosis, venous and arterial, inherited bleeding disorders, acquired bleeding disorders, blood groups and antibodies, safe and appropriate prescribing of blood products, complications of blood product transfusion, lymphadenopathy, Hodgkin and non-Hodgkin lymphomas, multiple myeloma and MGUS, acute and chronic leukaemias, myelodysplastic syndromes, myeloproliferative disorders.

Clinical Immunology

Immunodeficiency, autoimmunity and diagnosis of autoimmune disease, immunomodulation and immunosuppression, major histocompatibility complex and transplantation, allergy.

Clinical Biochemistry

Fluid and electrolyte balance, acid base disorders, calcium, phosphate, magnesium, bone and metabolism, enzymology, liver function, endocrine diseases, diabetes mellitus, gastrointestinal disease, inherited metabolic disorders and screening, lipid disorders, proteins - diagnostic uses, biochemical markers of central nervous system (CNS) diseases.

Teaching Methods

Delivery type Number Length hours Student hours
Lecture 78 1 78
Seminar 6 1 6
Tutorial 7 1 7
Independent online learning hours 80
Private study hours 48
Total Contact hours 91
Total hours (100hr per 10 credits) 219

Private study

Private study and independent learning will allow students to reflect upon and apply the information and knowledge they have discussed and explored in the teaching sessions they have attended. Students will also have access to a wide range of online resources to support their learning. Students are expected to complete eight hours of private study and online learning per week.

Opportunities for Formative Feedback

Students will have tutorials throughout the course, covering content from selected topics from the 11 themes covered on the course. The tutorials are designed to be interactive case presentations highlighting the key areas of the themes, and every student will be expected to contribute. Student progress will also be monitored through their performance in 11 online knowledge tests, one at the end of each theme.


The assessment strategy on the MBChB programme is based upon regular opportunities for assessment for learning (formative) with regular feedback in order to build students confidence and monitor progress. Assessment for learning in this module will comprise 11 on-line knowledge tests with instant feedback.

All students sit a formative exam paper approximately 4 weeks before the summative exam from which they receive a breakdown of scores for each ICU. This exam includes questions of equivalent format, standard and subject mix to those used in the year 2 final summative exam, including content taught in Clinical Pathology.

Exams
Exam type Exam duration % of formal assessment
Standard exam (closed essays, MCQs etc) 4.0 Hrs 0 Mins 100
Total percentage (Assessment Exams) 100

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading List

The reading list is available from the Library website

Last updated: 4/29/2024

Errors, omissions, failed links etc should be notified to the Catalogue Team