2025/26 Undergraduate Module Catalogue

BLGY2202 Bioinformatics for Biologists

10 Credits Class Size: 95

Module manager: Glenn McConkey
Email: G.A.McConkey@leeds.ac.uk

Taught: Semester 2 (Jan to Jun) View Timetable

Year running 2025/26

Pre-requisite qualifications

A level Biology

Module replaces

BLGY2201

This module is approved as a discovery module

Module summary

This module will introduce you to the fundamental concepts and techniques of bioinformatics, with a focus on applications relevant to biological research. This module will develop students’ skills to search and query publicly available biological databases of genome, sequence, structure, physical mapping and bibliographic, extract data and analyse and display results using appropriate software. Web accessible resources are used to ensure maximum transferability of the knowledge gained. The objective is to teach how to use available bioinformatic resources.

Objectives

This module aims to introduce students to the basic concepts of bioinformatics and illustrate the application of bioinformatics to many biological questions. The objective is to teach you how to use available bioinformatic resources to answer key biological questions. The module shows how genomic data is stored and accessed to learn about any characterised gene or protein and how it links to resources on research. The approaches to modern phylogenetics are introduced and how bioinformatics is applied to drug discovery.

Learning outcomes

On successful completion of the module students will have demonstrated the following learning outcomes relevant to the subject:

1) Identify and use appropriate publicly available biological databases of genome, sequence, structure, physical mapping and bibliographic information for gene and protein delineation.
2) perform searches and queries of relevant databases and extract data from these different databases
3) analyse and interpret bioinformatic data and display results using appropriate software. 

Skills Learning Outcomes

On successful completion of the module students will have demonstrated the following skills learning outcomes:

4) Apply problem-solving skills to digital processes and online workflows.

Syllabus

- Query and extraction of protein sequences and structures from major databases.
- Homology and conserved feature-based searching and interpretation of the results.
- Prediction and analysis of gene elements including coding and regulatory regions and prediction of secondary structures.
- Sequence alignment, identification of conserved residues and motifs. Phylogenetic analysis and tree analysis.
- Contig assembly and map location.
- Tissue-specific expression using EST databases and PCR primer design.
- Bibliographic searching of Medline (Pubmed).

Teaching Methods

Delivery type Number Length hours Student hours
Lecture 5 1 5
Practical 5 3 15
Independent online learning hours 20
Private study hours 60
Total Contact hours 20
Total hours (100hr per 10 credits) 100

Opportunities for Formative Feedback

Five formative assignment exercises (every week of class) based on Practical skills and learning from lectures. Individual feedback is provided. These are based on Computer-based Practical exercises linked to the lecture topic for that week. Individual exercise answers are checked for accuracy and guidance provided on how to improve. The skill set checked directly feeds into the Summative problem-set assignment.

Informal feedback is provided individually during Practical sessions.

Formative feedback from problems answered in Practicals will provide clarity on expectations for the Summative Assignment.

Methods of Assessment

Coursework
Assessment type Notes % of formal assessment
Coursework Summative problem set that applies skills gained in Practicals 100
Total percentage (Assessment Coursework) 100

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading List

There is no reading list for this module

Last updated: 05/03/2025

Errors, omissions, failed links etc should be notified to the Catalogue Team