2024/25 Undergraduate Module Catalogue

BIOL2212 Chemotherapy

10 Credits Class Size: 210

Module manager: Professor Alex O'Neill
Email: A.J.ONeill@leeds.ac.uk

Taught: Semester 2 (Jan to Jun) View Timetable

Year running 2024/25

Pre-requisite qualifications

Successful completion of level 1 in a biological subject

Module replaces

BMSC2210 Chemotherpy, 10c,

This module is not approved as a discovery module

Module summary

The basis of chemotherapy is selective toxicity, the use of agents to kill or suppress the growth of invading cells or infective organisms. This module will help you understand how these agents work. You will learn about the drugs used to treat cancer, bacterial, fungal and viral infections. In addition, immunosuppressant drugs and the chemotherapy of protozoal diseases such as malaria will also be discussed.

Objectives

To provide an introduction to the principles of chemotherapy and to examine in detail the mechanisms by which chemotherapeutic drugs act. The module will also address a range of other relevant aspects (e.g. how are chemotherapeutic agents selected for treatment of a particular disease, how are they administered to patients, and what are the issues that hinder their use?), thereby collectively providing detailed insights into this topic. This information will be imparted to students exclusively through lectures.

Learning outcomes

On completion of the module, students will be able to:
1. outline the aims and fundamental principles of chemotherapy
2. demonstrate a basic knowledge of pharmacokinetics as it relates to chemotherapy
3. discuss the nature of major disease types against which chemotherapy is deployed
4. understand the clinical application and mode of action of chemotherapeutic drugs employed in the treatment of infectious diseases (caused by bacteria, viruses and fungi) and cancer
5. explain the nature, origins and mechanisms of resistance to chemotherapeutic drugs

Skills outcomes

Improved ability to research literature and solve problems related to chemotherapy.

Syllabus

Aims and fundamental principles of chemotherapy
Basic pharmacokinetics
Nature of major disease types against which chemotherapy is deployed
Clinical application and mode of action of major chemotherapeutic drugs employed in the treatment of cancer and infectious diseases caused by bacteria, viruses and fungi
Nature, origins and mechanisms of resistance to chemotherapeutic drugs

Teaching Methods

Delivery type Number Length hours Student hours
In Course Assessment 1 1 1
Lecture 19 1 19
Private study hours 80
Total Contact hours 20
Total hours (100hr per 10 credits) 100

Private study

- Two hours reading per lecture: 34 hours
- Preparation for end of module examination and in-course MRQ: 45 hours.

Opportunities for Formative Feedback

- 20 question self-assessed MRQ in Minerva
- In-course assessment
- Group feedback on in-course assessment
- Student attendance at lectures will be monitored in line with standard faculty practice

Methods of Assessment

Coursework
Assessment type Notes % of formal assessment
In-course MCQ 30 questions - in person closed-book MRQ test accessed via Mineva 20
Total percentage (Assessment Coursework) 20

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Exams
Exam type Exam duration % of formal assessment
Online MCQ 1.0 Hrs Mins 24
Online Time-Limited assessment 2.0 Hrs Mins 56
Total percentage (Assessment Exams) 80

Online MCQ: This will be an in person closed-book MRQ test accessed via Minerva

Reading List

The reading list is available from the Library website

Last updated: 5/13/2024

Errors, omissions, failed links etc should be notified to the Catalogue Team